Randomized controlled trial of the effects of high-dose ondansetron on clinical symptoms and brain connectivity in obsessive-compulsive and tic disorders / Emily R. Stern en The American Journal of Psychiatry, Año 2025 - Vol. 182 - No.3 (Marzo)

Público ISBD [artículo]  inThe American Journal of Psychiatry > Año 2025 - Vol. 182 - No.3 (Marzo) . - PP. 285–296 Título : Randomized controlled trial of the effects of high-dose ondansetron on clinical symptoms and brain connectivity in obsessive-compulsive and tic disorders Tipo de documento: texto impreso Autores: Emily R. Stern, Autor ; Katherine A Collins, Autor ; Laura B. Bragdon, Autor Fecha de publicación: 2025 Artículo en la página: PP. 285–296 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Estudios clínicos con fármacos, Neuroimagen, Trastorno obsesivo-compulsivo (TOC), Ondansetrón, Trastorno de Tourette. Resumen: Sensory phenomena (SP) are aversive sensations driving repetitive behaviors in obsessive-compulsive disorder (OCD) and Tourette’s disorder that are not well addressed by standard treatments. SP are related to the functioning of an interoceptive-sensorimotor circuit that may be modulated by the 5-HT3 receptor antagonist ondansetron. Link: ./index.php?lvl=notice_display&id=31591 [artículo] Randomized controlled trial of the effects of high-dose ondansetron on clinical symptoms and brain connectivity in obsessive-compulsive and tic disorders [texto impreso] / Emily R. Stern, Autor ; Katherine A Collins, Autor ; Laura B. Bragdon, Autor . - 2025 . - PP. 285–296. Idioma : Inglés (eng) Idioma original : Inglés (eng) in The American Journal of Psychiatry > Año 2025 - Vol. 182 - No.3 (Marzo) . - PP. 285–296 Palabras clave: Estudios clínicos con fármacos, Neuroimagen, Trastorno obsesivo-compulsivo (TOC), Ondansetrón, Trastorno de Tourette. Resumen: Sensory phenomena (SP) are aversive sensations driving repetitive behaviors in obsessive-compulsive disorder (OCD) and Tourette’s disorder that are not well addressed by standard treatments. SP are related to the functioning of an interoceptive-sensorimotor circuit that may be modulated by the 5-HT3 receptor antagonist ondansetron. Link: ./index.php?lvl=notice_display&id=31591

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